Table of Contents
Agenda
Friday, July 27th, 2018 9:30 – 3:00 PM
Van Nuys Atrium, 635 Barnhill Drive, Indianapolis, IN 46202
| 9:00am | Student Check-In and Poster Set Up for Session 1 |
| 9:30am | Welcome Brittney-Shea Herbert, PhD Assistant Dean for Physician Scientist Development Director, IMPRS |
| 9:45am | Opening Remarks Peter Nalin, MD Associate Dean and Interim Director, IUSM-Bloomington |
| 10am – 12pm | Poster Session 1
|
| 12pm | Student Check-In and Poster Set Up for Session 2 |
| 12:30pm | Welcome Brittney-Shea Herbert, PhD Assistant Dean for Physician Scientist Development Director, IMPRS |
| 12:45pm | Opening Remarks Anantha Shekhar, MD, PhD Executive Associate Dean of Research Affairs |
| 1pm – 3pm | Poster Session 2
|
List of Abstracts in Alphabetical Order
| First Name | Last Name | PROJECT TITLE |
| Nnamdi | Achebe | A TREM2 dependent control of Microglial and Astrocytic responses in a mouse model of Alzheimer’s Disease |
| Dana | Alhaffar | Efficacy and Safety of Fecal Microbiota Transplantation for the treatment of Clostridium difficile Infection in Patients with Liver Cirrhosis: a single center experience |
| Maaz | Arif | Inhibition of IRS-1 Alters Retinal Circadian Clock |
| Sam | Atoa | Assessment of nutrition status in transplant patients using imaging, serologic markers and functional testing: Which best predicts outcomes? |
| Joseph | Atumonye | Defining the Function of a Novel TNF Receptor Superfamily Member |
| Asma | Bahrami | Impact of excess TGFβ on bone and muscle in condition of diet-induced obesity in mice with Camurati-Engelmann Disease |
| Shivani | Bajpai | The effect of donor contrast exposure on recipient kidney outcomes |
| Joseph | Baker | The Examination of non-pharmacologic treatment of pain after spinal cord injury |
| Zachary | Barry | A Novel Small Molecule Therapy for Corneal Neovascularization |
| Dylan | Bieber | Effects of Propofol on Transcytosis in an IPSC Derived Blood Brain Barrier Model |
| Anthony | Boateng | Forever-Fit Summer Camp |
| Vyvian | Borse | Elevated Airway Eosinophils is Associated with Lower Airway Haemophilus |
| Abigail | Braun | CD33 and TREM2 Peripheral Gene Expression in Relation to Cortical Thickness |
| Cameron | Brown | Wound healing in diabetic Ossabaw pigs |
| Marissa | Bruce | Characterizing the Role of Orbitofrontal Cortex in Social Memory |
| Kendall | Burgett | The Influence of Aging on the Relationship between Retrobulbar Blood Flow and Retinal Microcirculation in Glaucoma Patients |
| Jarrett | Campbell | Quantifying Cigarette Smoke Induced Oxidative DNA Damage of Wild Type & XPC Knockdown Human Bronchial Cells Using Human 8-oxoguanine DNA Glycosylase 1 |
| Phillip | Cheng | Evaluating the effect of a Participatory Music Program on the Quality of Life and Community Reintegration of Homeless Veterans in Indianapolis |
| Monica | Cheng | A Clinically Suitable Approach to Whole-Body Imaging for Quantification of Regional Perfusion: Validation of Positron Emission Tomography (PET) with 62Cu-ETS and Image-based Tracer Kinetic Modeling |
| Kayla | Chin | Time to Diagnosis of Early-Onset vs. “Late-Onset” Colorectal Cancer: Is there a difference? |
| Diane | Choi | Establishing a Comprehensive Ethics-Based Checklist for Surgical Camp Activities at AMPATH-Kenya |
| Colette | Ciresi | Assessing generalizability of a new-onset type 1 diabetes Biobank |
| Nicholas | Clough | Role of CaMKK2 in Osteocytes within the Bone Microenvironment |
| Jacob | Davis | Canines in the emergency department: a novel approach to stress reduction in emergency medicine providers |
| Elizabeth | Davis | Examining Gross Anatomy Study Strategies Across Old and New Curricula |
| Anthony | Douglas II | Skin Sympathetic Nerve Activity and Rate Control of Atrial Fibrillation |
| Anna | Dudley | Determining the cellular localization of C.elegans Editing Enzyme |
| Cameron | Duffner | Quantitative Effect of Emergency Department Case Management on Visits, Diagnostics, and Cost |
| Damon | Edgar | A Case-Based Tropical Medicine Curriculum for Interdisciplinary Global Health Track Residents |
| Katarina | Fabre | Lung Ultrasound Proficiency Study |
| Alexander | Farmer | Genoproteomic analysis of leukemic cell response to Cytarabine reveals synergistic opportunities centered on cholesterol metabolism |
| Rick | Foust | Aspergeillus Fumigatus: The Effects of Adiponectin on Inflammatory Cytokine Production |
| Brandon | Francis | Assessing Student Engagement and Higher Order Skill Proficiency During the First and Second Year of Medical School – A Comparison Between the Legacy and Recently Reformed Active Learning Curricula |
| Colin | Fry | Humble But Powerful: The Role of “Access to Information & Knowledge” in Implementation Success in the RE-INSPIRE Study |
| Eric | Galante | Effect of Frataxin Knockout on Mouse Cardiomyocytes |
| Jarrell | Gary | Is Liver Function Homogenous? Correlation between CT Liver Volumes and Liver Function as Determined by Functional Hepatobiliary (HIDA) Scan |
| Rolando Gabriel | Gerena | Marginal Utility of Additional Clinical Shifts on Milestone-Based Competency in an Emergency Medicine Clerkship |
| Daniel | Gibson | Medical Students’ Studying Approach to a Changing Medical School Anatomy Curriculum |
| Briana | Grisby | Developmental Toxicity of TCE Exposure in Zebrafish: Analyzing Vitamin D Metabolism |
| Justin | Hendrix | Characterizing the Extent of Cell Death in Innate Immune Mediated Colitis |
| Emily | Hentz | Assessing lead exposure sources at the property scale in Indianapolis |
| Erik | Holder | Is Operative Diagnosis for Revision Total Hip Arthroplasty Related to Patient Reported Outcomes? |
| Gage | Howard | Fat Soluble Vitamin, B12 and Iron Deficiency in Patients with Coliform Small Intestinal Bacterial Overgrowth (SIBO) |
| Stephan | Hu | Validating a Novel Technique for Identifying Genomic Regulators |
| Nathan | Jarrett | Tendon transfer of pronator teres to flexor pollicis longus to restore thumb flexion in incomplete tetraplegia |
| Olivia | Johnson | Blueberry containing diets protect from bone loss induced by sex steroid deficiency differently depending on sex and by mechanisms independent of canonical sex steroid receptor signaling |
| Jordan | Jones | Leukocyte Localization in a Model of Innate Immune-Driven Colitis |
| Alexandra | Jostes | Birth Spacing and Family Planning: Implementation of enhanced education and training for Community Health Coaches |
| Courtney | Keilman | Resiliency in Medical Students and Residents Participating in the Global Health AMPATH Kenya Elective |
| Cutter | Koehler | Impact of Hepatic Stellate Cells in Scaffold-Free 3D-Bioprinting of the Liver Model |
| Kaleb | Kramer | Are there sex-based differences in myocardial injury in Acute Heart Failure? |
| Nathan | Lam | Mapping Out Receptors: High Throughput Screening of Endothelial Monocyte Activating Polypeptide II (EMAPII) Using PRESTO-TANGO |
| Regina | Lee | Store operated calcium entry in diabetic macrophages is reduced in fasting conditions |
| Alexa | Loncharich | Type 2 Diabetes Mouse Model: Insights into the Contribution of Metabolic Defects to Neurocognitive Decline |
| Samuel | Lorentz | Genetic Defects in SHROOM3 Lead to Congenital Heart Defects |
| Samuel | Luebbe | Cardiovascular Effects of Sodium Glucose Cotransporter-2 (SGLT-2) Inhibition in the Setting of Ischemia/Reperfusion Injury |
| Joyce | Mannon | Fidelity of Peer Supported Self-Management of Chronic Pain (Evaluation of a Peer Coach-Led Intervention to Improve Pain Symptoms—ECLIPSE) |
| Mackenzie | McGrath | MELodica Orchestra for DYspnea (MELODY): A Randomized Safety, Feasibility, and Efficacy Pilot |
| Anthony | Milto | Evaluation of a Critical Sized Bone Defect in a Porcine Tibial Model |
| Kalina | Misiolek | Understanding the Algebraic and Logical Structure of Speech Perception; Effect of Signal-Dependent Noise on Phase Synchrony Pattern |
| Amer | Mohiuddin | REDUCED INFECTION RATE AFTER ASEPTIC REVISION TOTAL HIP ARTHROPLASTY WITH EXTENDED ORAL ANTIBIOTIC PROTOCOL |
| Hannah | Moore | SILDENAFIL IS NOT PROTECTIVE TO THE BOWEL FOLLOWING INTESTINAL ISCHEMIA AND REPERFUSION INJURY |
| Mumtaz | Munshi | Impact of ED Scribes in a Residency Program |
| David | Muschi | Disease Severity in Non-alcoholic Fatty Liver Disease (NAFLD) Patients with No Prior Diagnosis of Cirrhosis – A Unique Insight Using Vibration-Controlled Transient Elastography (VCTE) |
| Amit | Nag | Association of AHI and Other Patient Factors with Calvarial Thickness |
| Sharle | Newman | Role of CCL21 on the Transcriptional Regulation of MHC II in Malignant Glioma Infiltrating Plasmacytoid Dendritic Cells |
| Will | Northquist | A Case-Based Tropical Medicine Curriculum for Interdisciplinary Global Health Track Residents |
| Chiagozie | Nwosu | The Degradation and Subcellular Localization of an Oncogenic protein complex in T-cell Leukemia |
| Obi | Nwosu | Using RNA Editing and ADARs to Increase Cell Sensitivity to Interferon Chemotherapies |
| Max | Ofoma | Patient Perception of Empathy from Emergency Medicine Residents |
| William | O’Neal | Are signaling pathways inversely regulated in Alzheimer’s disease and glioblastoma multiforme? |
| Zachary | Osborn | Decreased Dynamic Flexibility of Brain Functional Connectivity in Prodromal Alzheimer’s Disease |
| Vitalis | Osuji | Role of Endoscopic Retrograde CholangioPancreatography (ERCP) and Intraductal Secretin Test (IDST) in the Diagnosis of Chronic Pancreatitis (CP) |
| Chirag | Patel | Fecal Bile Acids and Fecal Short Chain Fatty Acids in Patients with Irritable Bowel Syndrome and Control Volunteers |
| Roshni | Patel | Combined inhibition of Bruton’s Tyrosine Kinase (BTK) and Phosphoinositide 3-kinase (PI3K) p110δ improves monocytosis and splenomegaly in a JMML Mouse Model |
| Michael | Peng | Surveying ADR knowledge and practices among US gastroenterologists |
| Alexander | Peters | Minimally Invasive, Non-Terminal In Vivo Muscle Testing of a Porcine Tibia Fracture Model |
| Whitney | Phillips | Outcome of Pediatric Emergency Point-of-Care Ultrasound (POCUS) for Management of Skin and Soft Tissue Infection Prior to Ultrasound Program Implementation |
| Michelle | Pinto | Anxiety Screening in the Emergency Department |
| Ruben | Prado | Identification of genes and molecular pathways involved in a C. elegans model of neuroborreliosis |
| Eric | Regele | Immune regulation of neuronal injury and repair by observing T cell activation |
| Kathryn | Reinhart | The risk of bleeding following therapeutic endoscopy is low in patients with cirrhosis |
| Justin | Rice | Early Pain, Narcotic Use, and Functional Recovery in Aseptic Revision Total Knee Arthroplasty Performed with Morphine Spinal Analgesia versus Fentanyl Spinal Analgesia with Adductor Canal Block |
| Brad | Rumancik | Comparison of two techniques using EUS guided liver biopsies via 19g core biopsy needle to obtain optimal core specimen in benign disease |
| Sydney | Ryckman | Attitudes toward Contraception Initiation in the Emergency Department among Providers and Patients |
| Katlyn | Sawyer | Utilizing Citizen Science to Reverse the Current Lead Testing Paradigm: Development of a Scalable, Low-cost Home Lead Test Kit |
| Anna | Scalzo | Increasing Adolescents’ Access to the HIV Continuum of Care: Development of a Screening Tool for Medical Legal Partnerships |
| Lauren | Schmidt | Determining Health Utilities for Immunosuppression in Pediatric Inflammatory Bowel Disease |
| Christian | Schmidt | Reversal of Severe Sarcopenia in Pediatric Liver Failure Patients Post-Transplant |
| Adam | Schmitz | Transjugular Intrahepatic Portosystemic Shunt (TIPS) Creation to Improve Surgical Candidacy Prior to Abdominal Operation: A Retrospective Analysis |
| Paige | Schultheis | Copy Number Analysis of Lung Tumor Progression in Mice |
| Nicole | Shammas | The Association of Haptoglobin Genotype with the Development of Liver Disease and a Strategy for Personalized Treatment of NASH |
| Mitra | Sharifi | Effect of Tyrosine Phosphorylation of HPV31 E2 on Replication |
| Andrew | Shearn | Pneumonia in Indiana nursing homes: a retrospective case series |
| Christian | Sikoski | Predictors of Patient Function, Pain, and Satisfaction after Reimplantation for Infected Hip and Knee Arthroplasty |
| Blake | Simon | Modulation of Myocardial Oxygen Delivery in Response to Isovolemic Hemodilution |
| Sandeep | Singh | Enhancing cytotoxic chemotherapy response through targeted BET bromodomain inhibition in preclinical pancreatic cancer models |
| Dana | Skold | A Descriptive Time Inventory of Emergency Department Nursing Workflows |
| Ryan | Smith | Chamas for Change: A Community Based Strategy for Pregnancy, Infancy, and Women Empowerment |
| Hajeung (Leo) | Song | Senescent T cell population in Glioblastoma |
| Henry | Stadler | Investigating the role of COQ8B in aortic smooth muscle cells |
| Kyle | Stucker | IL-6 Stimulates Autophagy in Wild Type and NRF2 Knock Out Mice β-cells |
| Madison | Tenbarge | Determining if Double Gene Knockdown of P65 and PDK2 Increases Cytotoxicity and Radiation Sensitivity of Pancreatic Cancer Cells |
| Hannah | Thielmeyer | Control of Chemotherapy-Induced Peripheral Neuropathy and HMGB1 Cytosolic Translocation in Dorsal Root Ganglion Sensory Neurons Using Olaparib |
| Cody | Tragesser | Early surgical intervention is indicated for recurrent spontaneous pneumothorax in children and adolescents |
| Brady | Tucker | SOX-2 Mediated Conversion of Astrocyte to Neuron |
| Roziya | Tursunova | Clinical and radiographic factors associated with appendectomy in pediatric patients with abdominal pain and equivocal imaging findings for appendicitis |
| Gary | Ulrich | Current Concepts in the Treatment of Patellofemoral Instability |
| Juan | Valdes | Molecular characteristics of serum hepatitis B virus (HBV) RNA: a novel biomarker for chronic HBV infection |
| Madalyn | Vonderohe | Starting from the Roots: Observing Healthcare and Population Health Endeavors in a Lower Middle Income Country |
| Brett | Walker | Enhanced survival of lethally irradiated mice given pegylated G-CSF, GM-CSF, and IL-11 with lisinopril via modulation of the hematopoietic cytokines TGFb-1 and RANTES |
| Sarah | Watkins | BabyNoggin Pre-implementation Phase: Understanding How Clinical Teams and Parents Will Respond to BabyNoggin |
| Jonathan | Wheeler | Gabapentin Targeting and Bone Mineralization Defects: Proposed mechanism for increased fracture risk in patients taking GBP-class anti-epileptic drugs |
| Michael | Wiley | Effects of Temperature and Separation on the Retained Coagulability of Human Blood Utilizing Thromboelastography |
| Reid | Wilson | Quantifying the effects of mechanical signals on musculoskeletal quality in a model of complete estrogen deprivation |
| Honglin | Xiao | Blood Loss in Primary and Aseptic Revision Total Knee Arthroplasty: A Retrospective Matched Cohort Analysis |
| Stephanie | Younker | This Story Needs to Be Told: Formative Research on Using Animated Storytelling to Address Prospective Minority Clinical Trials Participants’ Need for Comprehensive Knowledge |
| Kirsten | Zborek | A Physiological Role for a Moonlighting Protein in Lipopolysaccharide-induced Endotoxemia |
Finalists and Honorable Mentions
We would like to congratulate all the students and faculty who participated in the 2018 IMPRS Program. The program’s mission is to provide a wide range of research and scholarly opportunities to the IUSM student body. The purpose is to enrich the research and scholarly education and knowledge for the medical students. This summer we hosted 103 medical students from all 9 campuses doing research and scholarly activities in the areas of: laboratory and translational research, clinical research, health research outcomes and community health education. During the summer, the student worked with their assigned mentor at the designated campus on a project they have derived and planned. Each week, students attended a Seminar Series to learn about different research topics as well as responsible conduct of research, career development and work/life balance. At the end of the summer session, students participated in the poster session. The event showcased 118 posters of projects completed by the IUSM medical students Class of 2021. Each student presented their project to the faculty judges who have volunteered their time to be a part of this event. We want to congratulate and recognize the following students who were selected to do the oral presentation on August 1 and to the students who received Honorable Mention.
Finalists
| Student’s Name | Mentor |
|---|---|
| Alexander Peters | Melissa Kacena |
| Amit Nag | Rick Nelson |
| Andrew Shearn | Jennifer Carnahan |
| Blake Simon | Johnathan Tune |
| Brandon Francis | Mari Hopper |
| Collete Ciresi | Linda DiMeglio |
| Cutter Koehler | Bursin Ekser |
| David Muschi | Raj Vuppalanchi |
| Emily Hentz | Gabriel Filipelli |
| Hannah M. Moore | Troy Markel |
| Johnathan Wheeler | Kenneth White |
| Kalina Misiolek | Leonid Rubchinsky and Robert M. Worth |
| Katlyn Sawyer | Heidi Beidinger |
| Samuel Luebbe | Johnathan Tune |
| Maaz Arif | Ashay Bhatwadekar |
| Marissa Bruce | William Truitt |
| Monica Cheng | Gary Hutchins |
| Roshni Patel | Reuben Kapur |
| Stephan Hu | Yunlong Liu |
| Whitney Phillips | Benjamin Nti |
Honorable Mentions
| Student’s Name | Mentor |
|---|---|
| Anna C Scalzo | Amy Lewis-Gilbert |
| Anthony Douglas II | Peng Chen |
| Brett Walker | Christie Orschell |
| Cameron Duffner and Xyryl Pablo | Jeffrey Nickel |
| Daniel Gibson | Polly Husmann |
| Eric Galante | Mark Payne |
| Gary Ulrich | Hemant Pandit |
| Henry Stadler | Stephanie Ware |
| Alexandra Jostes | Debra Litzelman |
| Joyce Mannon | Marianne Matthias |
| Michael Wiley | Nathan Alves |
| Mumtaz Munshi | Daniel Corson-Knowles |
| Obi Nwosu | Heather Hundley |
| Paige Schultheis | Mark Geraci |
| Leo Song | Mahua Dey |
| Honglin Xiao | R. Michael Meneghini |